Restoring Apoptosis with BH3 Mimetics in Mature B-Cell Malignancies

Apoptosis is a highly conserved mechanism enabling the removal of unwanted cells. Mitochondrial apoptosis is governed by the B-cell lymphoma (BCL-2) family, including anti-apoptotic and pro-apoptotic proteins. Apoptosis evasion by dysregulation of anti-apoptotic BCL-2 members (BCL-2, MCL-1, BCL-X(L)...

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Detalles Bibliográficos
Autores principales: Jullien, Maxime, Gomez-Bougie, Patricia, Chiron, David, Touzeau, Cyrille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140641/
https://www.ncbi.nlm.nih.gov/pubmed/32183335
http://dx.doi.org/10.3390/cells9030717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140641/
https://www.ncbi.nlm.nih.gov/pubmed/32183335
http://dx.doi.org/10.3390/cells9030717

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