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Pirfenidone Inhibits Cell Proliferation and Collagen I Production of Primary Human Intestinal Fibroblasts

Intestinal fibrosis is a common complication of inflammatory bowel disease. So far, there is no safe and effective drug for intestinal fibrosis. Pirfenidone is an anti-fibrotic compound available for the treatment of idiopathic pulmonary fibrosis. Here, we explored the anti-proliferative and anti-fi...

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Detalles Bibliográficos
Autores principales: Cui, Yingying, Zhang, Mengfan, Leng, Changsen, Blokzijl, Tjasso, Jansen, Bernadien H., Dijkstra, Gerard, Faber, Klaas Nico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140656/
https://www.ncbi.nlm.nih.gov/pubmed/32235767
http://dx.doi.org/10.3390/cells9030775