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Glioblastoma Multiforme Stem Cell Cycle Arrest by Alkylaminophenol through the Modulation of EGFR and CSC Signaling Pathways

Cancer stem cells (CSCs), a small subpopulation of cells existing in the tumor microenvironment promoting cell proliferation and growth. Targeting the stemness of the CSC population would offer a vital therapeutic opportunity. 3,4-Dihydroquinolin-1(2H)-yl)(p-tolyl)methyl)phenol (THTMP), a small synt...

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Detalles Bibliográficos
Autores principales: Doan, Phuong, Musa, Aliyu, Murugesan, Akshaya, Sipilä, Vili, Candeias, Nuno R., Emmert-Streib, Frank, Ruusuvuori, Pekka, Granberg, Kirsi, Yli-Harja, Olli, Kandhavelu, Meenakshisundaram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140667/
https://www.ncbi.nlm.nih.gov/pubmed/32164385
http://dx.doi.org/10.3390/cells9030681