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The Solo Play of TERT Promoter Mutations

The reactivation of telomerase reverse transcriptase (TERT) protein is the principal mechanism of telomere maintenance in cancer cells. Mutations in the TERT promoter (TERTp) are a common mechanism of TERT reactivation in many solid cancers, particularly those originating from slow-replicating tissu...

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Detalles Bibliográficos
Autores principales: Hafezi, François, Perez Bercoff, Danielle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140675/
https://www.ncbi.nlm.nih.gov/pubmed/32204305
http://dx.doi.org/10.3390/cells9030749