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Molecular and Pharmacological Modulation of CALHM1 Promote Neuroprotection against Oxygen and Glucose Deprivation in a Model of Hippocampal Slices

Calcium homeostasis modulator 1 (CALHM1) is a calcium channel involved in the regulation of cytosolic Ca(2+) levels. From a physiological point of view, the open state of CALHM1 depends not only on voltage but also on the extracellular concentration of calcium ([Ca(2+)]) ions. At low [Ca(2+)](e) or...

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Detalles Bibliográficos
Autores principales: Garrosa, Javier, Paredes, Iñigo, Marambaud, Philippe, G. López, Manuela, Cano-Abad, María F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140682/
https://www.ncbi.nlm.nih.gov/pubmed/32182953
http://dx.doi.org/10.3390/cells9030664