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A 3D Cell Death Assay to Quantitatively Determine Ferroptosis in Spheroids

The failure of drug efficacy in clinical trials remains a big issue in cancer research. This is largely due to the limitations of two-dimensional (2D) cell cultures, the most used tool in drug screening. Nowadays, three-dimensional (3D) cultures, including spheroids, are acknowledged to be a better...

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Detalles Bibliográficos
Autores principales: Demuynck, Robin, Efimova, Iuliia, Lin, Abraham, Declercq, Heidi, Krysko, Dmitri V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140689/
https://www.ncbi.nlm.nih.gov/pubmed/32183000
http://dx.doi.org/10.3390/cells9030703