An Overview on ERAP Roles in Infectious Diseases

Endoplasmic reticulum (ER) aminopeptidases ERAP1 and ERAP2 (ERAPs) are crucial enzymes shaping the major histocompatibility complex I (MHC I) immunopeptidome. In the ER, these enzymes cooperate in trimming the N-terminal residues from precursors peptides, so as to generate optimal-length antigens to...

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Detalles Bibliográficos
Autores principales: Saulle, Irma, Vicentini, Chiara, Clerici, Mario, Biasin, Mara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140696/
https://www.ncbi.nlm.nih.gov/pubmed/32183384
http://dx.doi.org/10.3390/cells9030720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140696/
https://www.ncbi.nlm.nih.gov/pubmed/32183384
http://dx.doi.org/10.3390/cells9030720

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