Interferon-β Stimulation Elicited by the Influenza Virus Is Regulated by the Histone Methylase Dot1L through the RIG-I-TRIM25 Signaling Axis

Influenza virus infection increases the methylation of lysine 79 of histone 3 catalyzed by the Dot1L enzyme. The role of Dot1L against infections was highlighted by an increase of influenza A and vesicular stomatitis virus replication in Dot1L-inhibited cells mediated by a decreased antiviral respon...

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Detalles Bibliográficos
Autores principales: Marcos-Villar, Laura, Nistal-Villan, Estanislao, Zamarreño, Noelia, Garaigorta, Urtzi, Gastaminza, Pablo, Nieto, Amelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140698/
https://www.ncbi.nlm.nih.gov/pubmed/32188146
http://dx.doi.org/10.3390/cells9030732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140698/
https://www.ncbi.nlm.nih.gov/pubmed/32188146
http://dx.doi.org/10.3390/cells9030732

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