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Interferon-β Stimulation Elicited by the Influenza Virus Is Regulated by the Histone Methylase Dot1L through the RIG-I-TRIM25 Signaling Axis
Influenza virus infection increases the methylation of lysine 79 of histone 3 catalyzed by the Dot1L enzyme. The role of Dot1L against infections was highlighted by an increase of influenza A and vesicular stomatitis virus replication in Dot1L-inhibited cells mediated by a decreased antiviral respon...
Autores principales: | Marcos-Villar, Laura, Nistal-Villan, Estanislao, Zamarreño, Noelia, Garaigorta, Urtzi, Gastaminza, Pablo, Nieto, Amelia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140698/ https://www.ncbi.nlm.nih.gov/pubmed/32188146 http://dx.doi.org/10.3390/cells9030732 |
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