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Haploinsufficient Rock1(+/−) and Rock2(+/−) Mice Are Not Protected from Cardiac Inflammation and Postinflammatory Fibrosis in Experimental Autoimmune Myocarditis

Progressive cardiac fibrosis is a common cause of heart failure. Rho-associated, coiled-coil-containing protein kinases (ROCKs) have been shown to enhance fibrotic processes in the heart and in other organs. In this study, using wild-type, Rock1(+/−) and Rock2(+/−) haploinsufficient mice and mouse m...

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Detalles Bibliográficos
Autores principales: Tkacz, Karolina, Rolski, Filip, Czepiel, Marcin, Działo, Edyta, Siedlar, Maciej, Eriksson, Urs, Kania, Gabriela, Błyszczuk, Przemysław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140701/
https://www.ncbi.nlm.nih.gov/pubmed/32178482
http://dx.doi.org/10.3390/cells9030700