Cargando…
Haploinsufficient Rock1(+/−) and Rock2(+/−) Mice Are Not Protected from Cardiac Inflammation and Postinflammatory Fibrosis in Experimental Autoimmune Myocarditis
Progressive cardiac fibrosis is a common cause of heart failure. Rho-associated, coiled-coil-containing protein kinases (ROCKs) have been shown to enhance fibrotic processes in the heart and in other organs. In this study, using wild-type, Rock1(+/−) and Rock2(+/−) haploinsufficient mice and mouse m...
Autores principales: | Tkacz, Karolina, Rolski, Filip, Czepiel, Marcin, Działo, Edyta, Siedlar, Maciej, Eriksson, Urs, Kania, Gabriela, Błyszczuk, Przemysław |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140701/ https://www.ncbi.nlm.nih.gov/pubmed/32178482 http://dx.doi.org/10.3390/cells9030700 |
Ejemplares similares
-
Angiotensin II receptor 1 controls profibrotic Wnt/β-catenin signalling in experimental autoimmune myocarditis
por: Czepiel, Marcin, et al.
Publicado: (2021) -
WNT/β-Catenin Signaling Promotes TGF-β-Mediated Activation of Human Cardiac Fibroblasts by Enhancing IL-11 Production
por: Działo, Edyta, et al.
Publicado: (2021) -
T Lymphocyte-Derived Exosomes Transport MEK1/2 and ERK1/2 and Induce NOX4-Dependent Oxidative Stress in Cardiac Microvascular Endothelial Cells
por: Rolski, Filip, et al.
Publicado: (2022) -
WNT3a and WNT5a Transported by Exosomes Activate WNT Signaling Pathways in Human Cardiac Fibroblasts
por: Działo, Edyta, et al.
Publicado: (2019) -
Heart non-specific effector CD4(+) T cells protect from postinflammatory fibrosis and cardiac dysfunction in experimental autoimmune myocarditis
por: Zarak-Crnkovic, Martina, et al.
Publicado: (2019)