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O-acetylated Gangliosides as Targets for Cancer Immunotherapy

O-acetylation of sialic acid residues is one of the main modifications of gangliosides, and modulates ganglioside functions. O-acetylation of gangliosides is dependent on sialyl-O-acetyltransferases and sialyl-O-acetyl-esterase activities. CAS1 Domain-Containing Protein 1 (CASD1) is the only human s...

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Detalles Bibliográficos
Autores principales: Cavdarli, Sumeyye, Delannoy, Philippe, Groux-Degroote, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140702/
https://www.ncbi.nlm.nih.gov/pubmed/32192217
http://dx.doi.org/10.3390/cells9030741