Oral Administration of Alpha Linoleic Acid Rescues Aβ-Induced Glia-Mediated Neuroinflammation and Cognitive Dysfunction in C57BL/6N Mice

In this work, we evaluated the effects of alpha linoleic acid (ALA), an omega-3 polyunsaturated fatty acid, on amyloid-beta-induced glial-cell-mediated neuroinflammation, amyloidogenesis, and cognitive dysfunction in mice. After an infusion of Aβ(1–42) (Aβ(1–42), 5 μL/5 min/mouse, intracerebroventri...

Descripción completa

Detalles Bibliográficos
Autores principales: Ali, Waqar, Ikram, Muhammad, Park, Hyun Young, Jo, Min Gi, Ullah, Rahat, Ahmad, Sareer, Abid, Noman Bin, Kim, Myeong Ok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140708/
https://www.ncbi.nlm.nih.gov/pubmed/32182943
http://dx.doi.org/10.3390/cells9030667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140708/
https://www.ncbi.nlm.nih.gov/pubmed/32182943
http://dx.doi.org/10.3390/cells9030667

Ejemplares similares