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A Wnt-BMP4 Signaling Axis Induces MSX and NOTCH Proteins and Promotes Growth Suppression and Differentiation in Neuroblastoma

The Wnt and bone morphogenetic protein (BMP) signaling pathways are known to be crucial in the development of neural crest lineages, including the sympathetic nervous system. Surprisingly, their role in paediatric neuroblastoma, the prototypic tumor arising from this lineage, remains relatively unch...

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Detalles Bibliográficos
Autores principales: Szemes, Marianna, Melegh, Zsombor, Bellamy, Jacob, Greenhough, Alexander, Kollareddy, Madhu, Catchpoole, Daniel, Malik, Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140810/
https://www.ncbi.nlm.nih.gov/pubmed/32210188
http://dx.doi.org/10.3390/cells9030783