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Supercoiling, R-Loops, Replication and the Functions of Bacterial Type 1A Topoisomerases

Type 1A topoisomerases (topos) are the only topos that bind single-stranded DNA and the only ones found in all cells of the three domains of life. Two subfamilies, topo I and topo III, are present in bacteria. Topo I, found in all of them, relaxes negative supercoiling, while topo III acts as a deca...

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Detalles Bibliográficos
Autores principales: Brochu, Julien, Breton, Émilie-Vlachos, Drolet, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140829/
https://www.ncbi.nlm.nih.gov/pubmed/32120891
http://dx.doi.org/10.3390/genes11030249