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Supercoiling, R-Loops, Replication and the Functions of Bacterial Type 1A Topoisomerases
Type 1A topoisomerases (topos) are the only topos that bind single-stranded DNA and the only ones found in all cells of the three domains of life. Two subfamilies, topo I and topo III, are present in bacteria. Topo I, found in all of them, relaxes negative supercoiling, while topo III acts as a deca...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140829/ https://www.ncbi.nlm.nih.gov/pubmed/32120891 http://dx.doi.org/10.3390/genes11030249 |