Impaired Replication Timing Promotes Tissue-Specific Expression of Common Fragile Sites

Common fragile sites (CFSs) are particularly vulnerable regions of the genome that become visible as breaks, gaps, or constrictions on metaphase chromosomes when cells are under replicative stress. Impairment in DNA replication, late replication timing, enrichment of A/T nucleotides that tend to for...

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Detalles Bibliográficos
Autores principales: Maccaroni, Klizia, Balzano, Elisa, Mirimao, Federica, Giunta, Simona, Pelliccia, Franca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140878/
https://www.ncbi.nlm.nih.gov/pubmed/32204553
http://dx.doi.org/10.3390/genes11030326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140878/
https://www.ncbi.nlm.nih.gov/pubmed/32204553
http://dx.doi.org/10.3390/genes11030326

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