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Switching from Fatty Acid Oxidation to Glycolysis Improves the Outcome of Acute‐On‐Chronic Liver Failure

Acute‐on‐chronic liver failure (ACLF) has a high mortality rate. Metabolic reprogramming is an important mechanism for cell survival. Herein, the metabolic patterns of ACLF patients are analyzed. An in vitro model of ACLF is established using Chang liver cells under hyperammonemia and hypoxia. A ran...

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Detalles Bibliográficos
Autores principales: Yu, Zujiang, Li, Jingjing, Ren, Zhigang, Sun, Ranran, Zhou, Yang, Zhang, Qi, Wang, Qiongye, Cui, Guangying, Li, Juan, Li, Ang, Duan, Zhenfeng, Xu, Yuming, Wang, Zhichao, Yin, Peiyuan, Piao, Hailong, Lv, Jun, Liu, Xiaorui, Wang, Yanfang, Fang, Ming, Zhuang, Zhengping, Xu, Guowang, Kan, Quancheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141014/
https://www.ncbi.nlm.nih.gov/pubmed/32274306
http://dx.doi.org/10.1002/advs.201902996