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Smart Hydrogels for the Augmentation of Bone Regeneration by Endogenous Mesenchymal Progenitor Cell Recruitment

The treatment of bone defects with recombinant bone morphogenetic protein‐2 (BMP‐2) requires high doses precluding broad clinical application. Here, a bioengineering approach is presented that strongly improves low‐dose BMP‐2‐based bone regeneration by mobilizing healing‐associated mesenchymal proge...

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Detalles Bibliográficos
Autores principales: Lienemann, Philipp S., Vallmajo‐Martin, Queralt, Papageorgiou, Panagiota, Blache, Ulrich, Metzger, Stéphanie, Kiveliö, Anna‐Sofia, Milleret, Vincent, Sala, Ana, Hoehnel, Sylke, Roch, Aline, Reuten, Raphael, Koch, Manuel, Naveiras, Olaia, Weber, Franz E., Weber, Wilfried, Lutolf, Matthias P., Ehrbar, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141038/
https://www.ncbi.nlm.nih.gov/pubmed/32274319
http://dx.doi.org/10.1002/advs.201903395