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CRISPR-Generated Animal Models of Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is a fatal X-linked recessive neuromuscular disorder most commonly caused by mutations disrupting the reading frame of the dystrophin (DMD) gene. DMD codes for dystrophin, which is critical for maintaining the integrity of muscle cell membranes. Without dystrophin,...

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Detalles Bibliográficos
Autores principales: Lim, Kenji Rowel Q., Nguyen, Quynh, Dzierlega, Kasia, Huang, Yiqing, Yokota, Toshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141101/
https://www.ncbi.nlm.nih.gov/pubmed/32213923
http://dx.doi.org/10.3390/genes11030342