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Epigenetic Modification of CFTR in Head and Neck Cancer

Cystic fibrosis transmembrane conductance regulator (CFTR), a cyclic AMP (cAMP)-regulated chloride channel, is critical for secretion and absorption across diverse epithelia. Mutations or absence of CFTR result in pathogeneses, including cancer. While CFTR has been proposed as a tumor suppressing ge...

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Detalles Bibliográficos
Autores principales: Shin, Yonghwan, Kim, Minkyoung, Won, Jonghwa, Kim, Junchul, Oh, Seog Bae, Lee, Jong-Ho, Park, Kyungpyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141320/
https://www.ncbi.nlm.nih.gov/pubmed/32182826
http://dx.doi.org/10.3390/jcm9030734