Glucocerebrosidase: Functions in and Beyond the Lysosome

Glucocerebrosidase (GCase) is a retaining β-glucosidase with acid pH optimum metabolizing the glycosphingolipid glucosylceramide (GlcCer) to ceramide and glucose. Inherited deficiency of GCase causes the lysosomal storage disorder named Gaucher disease (GD). In GCase-deficient GD patients the accumu...

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Detalles Bibliográficos
Autores principales: Boer, Daphne E.C., van Smeden, Jeroen, Bouwstra, Joke A., Aerts, Johannes M.F.G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141376/
https://www.ncbi.nlm.nih.gov/pubmed/32182893
http://dx.doi.org/10.3390/jcm9030736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141376/
https://www.ncbi.nlm.nih.gov/pubmed/32182893
http://dx.doi.org/10.3390/jcm9030736

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