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Losartan inhibits hyposmotic-induced increase of I(Ks) current and shortening of action potential duration in guinea pig atrial myocytes
OBJECTIVE: The present study aims to investigate the effect of losartan, an selective angiotensin II type 1 receptor (AT(1)R) blocker, on both the increase of I(Ks) current and shortening of action potential duration (APD) induced by stretch of atrial myocytes, and to uncover the mechanism underlyin...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Kare Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141430/ https://www.ncbi.nlm.nih.gov/pubmed/31911569 http://dx.doi.org/10.14744/AnatolJCardiol.2019.75332 |