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Losartan inhibits hyposmotic-induced increase of I(Ks) current and shortening of action potential duration in guinea pig atrial myocytes

OBJECTIVE: The present study aims to investigate the effect of losartan, an selective angiotensin II type 1 receptor (AT(1)R) blocker, on both the increase of I(Ks) current and shortening of action potential duration (APD) induced by stretch of atrial myocytes, and to uncover the mechanism underlyin...

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Detalles Bibliográficos
Autores principales:	Gao, Jie, Yun, Tian, Xie, Xiao-Lu, Zhao, Jin, Liu, Chuan-hao, Sheng, Ying, Cao, Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Kare Publishing 2020
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141430/ https://www.ncbi.nlm.nih.gov/pubmed/31911569 http://dx.doi.org/10.14744/AnatolJCardiol.2019.75332

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