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Enhancing diastolic function by strain-dependent detachment of cardiac myosin crossbridges

The force response of cardiac muscle undergoing a quick stretch is conventionally interpreted to represent stretching of attached myosin crossbridges (phase 1) and detachment of these stretched crossbridges at an exponential rate (phase 2), followed by crossbridges reattaching in increased numbers d...

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Detalles Bibliográficos
Autores principales: Palmer, Bradley M., Swank, Douglas M., Miller, Mark S., Tanner, Bertrand C.W., Meyer, Markus, LeWinter, Martin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141588/
https://www.ncbi.nlm.nih.gov/pubmed/32197271
http://dx.doi.org/10.1085/jgp.201912484