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Enhancing diastolic function by strain-dependent detachment of cardiac myosin crossbridges
The force response of cardiac muscle undergoing a quick stretch is conventionally interpreted to represent stretching of attached myosin crossbridges (phase 1) and detachment of these stretched crossbridges at an exponential rate (phase 2), followed by crossbridges reattaching in increased numbers d...
Autores principales: | Palmer, Bradley M., Swank, Douglas M., Miller, Mark S., Tanner, Bertrand C.W., Meyer, Markus, LeWinter, Martin M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141588/ https://www.ncbi.nlm.nih.gov/pubmed/32197271 http://dx.doi.org/10.1085/jgp.201912484 |
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