Cargando…

NMDA receptor channel gating control by the pre-M1 helix

The NMDA receptor (NMDAR) is an ionotropic glutamate receptor formed from the tetrameric assembly of GluN1 and GluN2 subunits. Within the flexible linker between the agonist binding domain (ABD) and the M1 helix of the pore-forming transmembrane helical bundle lies a two-turn, extracellular pre-M1 h...

Descripción completa

Detalles Bibliográficos
Autores principales: McDaniel, Miranda J., Ogden, Kevin K., Kell, Steven A., Burger, Pieter B., Liotta, Dennis C., Traynelis, Stephen F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141592/
https://www.ncbi.nlm.nih.gov/pubmed/32221541
http://dx.doi.org/10.1085/jgp.201912362