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Locus coeruleus norepinephrine activity mediates sensory-evoked awakenings from sleep

A defining feature of sleep is reduced responsiveness to external stimuli, but the mechanisms mediating sensory-evoked arousal remain unclear. We hypothesized that reduced locus coeruleus (LC) norepinephrine (NE) activity during sleep mediates unresponsiveness, and its action promotes sensory-evoked...

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Detalles Bibliográficos
Autores principales: Hayat, Hanna, Regev, Noa, Matosevich, Noa, Sales, Anna, Paredes-Rodriguez, Elena, Krom, Aaron J., Bergman, Lottem, Li, Yong, Lavigne, Marina, Kremer, Eric J., Yizhar, Ofer, Pickering, Anthony E., Nir, Yuval
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141817/
https://www.ncbi.nlm.nih.gov/pubmed/32285002
http://dx.doi.org/10.1126/sciadv.aaz4232