Cooperativity of K(v)7.4 channels confers ultrafast electromechanical sensitivity and emergent properties in cochlear outer hair cells

The mammalian cochlea relies on active electromotility of outer hair cells (OHCs) to resolve sound frequencies. OHCs use ionic channels and somatic electromotility to achieve the process. It is unclear, though, how the kinetics of voltage-gated ionic channels operate to overcome extrinsic viscous dr...

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Detalles Bibliográficos
Autores principales: Perez-Flores, Maria C., Lee, Jeong H., Park, Seojin, Zhang, Xiao-Dong, Sihn, Choong-Ryoul, Ledford, Hannah A., Wang, Wenying, Kim, Hyo Jeong, Timofeyev, Valeriy, Yarov-Yarovoy, Vladimir, Chiamvimonvat, Nipavan, Rabbitt, Richard D., Yamoah, Ebenezer N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141818/
https://www.ncbi.nlm.nih.gov/pubmed/32285007
http://dx.doi.org/10.1126/sciadv.aba1104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141818/
https://www.ncbi.nlm.nih.gov/pubmed/32285007
http://dx.doi.org/10.1126/sciadv.aba1104

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