Cargando…

The cohesin release factor Wapl interacts with Bub3 to govern SAC activity in female meiosis I

During mitotic prophase, cohesins are removed from chromosome arms by Wapl to ensure faithful sister chromatid separation. However, during female meiosis I, the resolution of chiasmata requires the proteolytic cleavage of cohesin subunit Rec8 along chromosome arms by Separase to separate homologs, a...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Changyin, Miao, Yilong, Cui, Zhaokang, ShiYang, Xiayan, Zhang, Yu, Xiong, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141834/
https://www.ncbi.nlm.nih.gov/pubmed/32284991
http://dx.doi.org/10.1126/sciadv.aax3969