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Episo: quantitative estimation of RNA 5-methylcytosine at isoform level by high-throughput sequencing of RNA treated with bisulfite

MOTIVATION: RNA 5-methylcytosine (m(5)C) is a type of post-transcriptional modification that may be involved in numerous biological processes and tumorigenesis. RNA m(5)C can be profiled at single-nucleotide resolution by high-throughput sequencing of RNA treated with bisulfite (RNA-BisSeq). However...

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Detalles Bibliográficos
Autores principales: Liu, Junfeng, An, Ziyang, Luo, Jianjun, Li, Jing, Li, Feifei, Zhang, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141862/
https://www.ncbi.nlm.nih.gov/pubmed/31794005
http://dx.doi.org/10.1093/bioinformatics/btz900