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PTGES/PGE(2) signaling links immunosuppression and lung metastasis in Gprc5a-knockout mouse model
Chronic inflammation has been linked to promotion of tumorigenesis and metastasis in lung. However, due to lack of a relevant animal model for characterization, the underlying mechanism remains elusive. Lung tumor suppressor gene Gprc5a-knockout (ko) mice are susceptible to lung inflammation, tumori...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142021/ https://www.ncbi.nlm.nih.gov/pubmed/32060421 http://dx.doi.org/10.1038/s41388-020-1207-6 |