Long-term voluntary running prevents the onset of symptomatic Friedreich’s ataxia in mice

The common clinical symptoms of Friedreich’s ataxia (FRDA) include ataxia, muscle weakness, type 2 diabetes and heart failure, which are caused by impaired mitochondrial function due to the loss of frataxin (FXN) expression. Endurance exercise is the most powerful intervention for promoting mitochon...

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Detalles Bibliográficos
Autores principales: Zhao, Henan, Lewellen, Bevan M., Wilson, Rebecca J., Cui, Di, Drake, Joshua C., Zhang, Mei, Yan, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142077/
https://www.ncbi.nlm.nih.gov/pubmed/32269244
http://dx.doi.org/10.1038/s41598-020-62952-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142077/
https://www.ncbi.nlm.nih.gov/pubmed/32269244
http://dx.doi.org/10.1038/s41598-020-62952-6

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