Imbalance in mitochondrial dynamics induced by low PGC-1α expression contributes to hepatocyte EMT and liver fibrosis

An imbalance in mitochondrial dynamics induced by oxidative stress may lead to hepatocyte epithelial mesenchymal transition (EMT) and liver fibrosis. However, the underlying molecular mechanisms have not been fully elucidated. This study investigated the role of mitochondrial dynamics in hepatocyte...

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Detalles Bibliográficos
Autores principales: Zhang, Linzhong, Zhang, Yanghao, Chang, Xinxiang, Zhang, Xiuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142080/
https://www.ncbi.nlm.nih.gov/pubmed/32269221
http://dx.doi.org/10.1038/s41419-020-2429-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142080/
https://www.ncbi.nlm.nih.gov/pubmed/32269221
http://dx.doi.org/10.1038/s41419-020-2429-9

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