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Imbalance in mitochondrial dynamics induced by low PGC-1α expression contributes to hepatocyte EMT and liver fibrosis
An imbalance in mitochondrial dynamics induced by oxidative stress may lead to hepatocyte epithelial mesenchymal transition (EMT) and liver fibrosis. However, the underlying molecular mechanisms have not been fully elucidated. This study investigated the role of mitochondrial dynamics in hepatocyte...
Autores principales: | Zhang, Linzhong, Zhang, Yanghao, Chang, Xinxiang, Zhang, Xiuying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142080/ https://www.ncbi.nlm.nih.gov/pubmed/32269221 http://dx.doi.org/10.1038/s41419-020-2429-9 |
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