Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation

Receptor interacting protein kinase 1 (RIPK1) regulates cell death and inflammatory responses downstream of TNFR1 and other receptors, and has been implicated in the pathogenesis of inflammatory and degenerative diseases. RIPK1 kinase activity induces apoptosis and necroptosis, however the mechanism...

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Detalles Bibliográficos
Autores principales: Laurien, Lucie, Nagata, Masahiro, Schünke, Hannah, Delanghe, Tom, Wiederstein, Janica L., Kumari, Snehlata, Schwarzer, Robin, Corona, Teresa, Krüger, Marcus, Bertrand, Mathieu J. M., Kondylis, Vangelis, Pasparakis, Manolis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142081/
https://www.ncbi.nlm.nih.gov/pubmed/32269263
http://dx.doi.org/10.1038/s41467-020-15466-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142081/
https://www.ncbi.nlm.nih.gov/pubmed/32269263
http://dx.doi.org/10.1038/s41467-020-15466-8

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