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Zinc finger protein 703 induces EMT and sorafenib resistance in hepatocellular carcinoma by transactivating CLDN4 expression

Metastasis is one of the most common reasons of hepatocellular carcinoma (HCC) death; however, the molecular mechanism underlying HCC metastasis remains incompletely defined. Here we report a new function of Zinc Finger Protein 703 (ZNF703), a member of the NET/NlZ family of zinc finger transcriptio...

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Detalles Bibliográficos
Autores principales: Wang, Hao, Xu, Hongfa, Ma, Feng, Zhan, Meixiao, Yang, Xiangyu, Hua, Shengni, Li, Wei, Li, Yong, Lu, Ligong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142083/
https://www.ncbi.nlm.nih.gov/pubmed/32269215
http://dx.doi.org/10.1038/s41419-020-2422-3