A general (11)C-labeling approach enabled by fluoride-mediated desilylation of organosilanes

Carbon-11 ((11)C) is one of the most ideal positron emitters for labeling bioactive molecules for molecular imaging studies. The lack of convenient and fast incorporation methods to introduce (11)C into organic molecules often hampers the use of this radioisotope. Here, a fluoride-mediated desilylat...

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Detalles Bibliográficos
Autores principales: Qu, Wenchao, Hu, Bao, Babich, John W., Waterhouse, Nicole, Dooley, Marybeth, Ponnala, Shashikanth, Urgiles, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142131/
https://www.ncbi.nlm.nih.gov/pubmed/32269227
http://dx.doi.org/10.1038/s41467-020-15556-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142131/
https://www.ncbi.nlm.nih.gov/pubmed/32269227
http://dx.doi.org/10.1038/s41467-020-15556-7

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