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A general (11)C-labeling approach enabled by fluoride-mediated desilylation of organosilanes
Carbon-11 ((11)C) is one of the most ideal positron emitters for labeling bioactive molecules for molecular imaging studies. The lack of convenient and fast incorporation methods to introduce (11)C into organic molecules often hampers the use of this radioisotope. Here, a fluoride-mediated desilylat...
Autores principales: | Qu, Wenchao, Hu, Bao, Babich, John W., Waterhouse, Nicole, Dooley, Marybeth, Ponnala, Shashikanth, Urgiles, Julie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142131/ https://www.ncbi.nlm.nih.gov/pubmed/32269227 http://dx.doi.org/10.1038/s41467-020-15556-7 |
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