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PAM3 protects against DSS-induced colitis by altering the M2:M1 ratio

Inflammation of the gastrointestinal tract contributes to the development of inflammatory bowel disease (IBD). Human IBD is modeled by administering dextran sulfate sodium (DSS) to mice. In humans and mice, inflammatory M1 macrophages contribute to the progression of IBD whereas immunosuppressive M2...

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Detalles Bibliográficos
Autores principales: Horuluoglu, Begum H., Kayraklioglu, Neslihan, Tross, Debra, Klinman, Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142137/
https://www.ncbi.nlm.nih.gov/pubmed/32269253
http://dx.doi.org/10.1038/s41598-020-63143-z