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PIN1 Provides Dynamic Control of MYC in Response to Extrinsic Signals

PIN1 is a phosphorylation-directed member of the peptidyl-prolyl cis/trans isomerase (PPIase) family that facilitates conformational changes in phosphorylated targets such as c-MYC (MYC). Following signaling events that mediate phosphorylation of MYC at Serine 62, PIN1 establishes structurally disti...

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Detalles Bibliográficos
Autores principales: Cohn, Gabriel M., Liefwalker, Daniel F., Langer, Ellen M., Sears, Rosalie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142217/
https://www.ncbi.nlm.nih.gov/pubmed/32300594
http://dx.doi.org/10.3389/fcell.2020.00224