Cotinine Enhances Fear Extinction and Astrocyte Survival by Mechanisms Involving the Nicotinic Acetylcholine Receptors Signaling

Fear memory extinction (FE) is an important therapeutic goal for Posttraumatic stress disorder (PTSD). Cotinine facilitates FE in rodents, in part due to its inhibitory effect on the amygdala by the glutamatergic projections from the medial prefrontal cortex (mPFC). The cellular and behavioral effec...

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Detalles Bibliográficos
Autores principales: Oliveros-Matus, Patricia, Perez-Urrutia, Nelson, Alvarez-Ricartes, Nathalie, Echeverria, Florencia, Barreto, George E., Elliott, James, Iarkov, Alexandre, Echeverria, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142247/
https://www.ncbi.nlm.nih.gov/pubmed/32300297
http://dx.doi.org/10.3389/fphar.2020.00303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142247/
https://www.ncbi.nlm.nih.gov/pubmed/32300297
http://dx.doi.org/10.3389/fphar.2020.00303

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