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Oxadiazole-Containing Macrocyclic Peptides Potentiate Azole Activity against Pathogenic Candida Species

Opportunistic pathogens of the genus Candida reign as the leading cause of mycotic disease and are associated with mortality rates greater than 40%, even with antifungal intervention. This is in part due to the limited arsenal of antifungals available to treat systemic fungal infections. Azoles have...

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Detalles Bibliográficos
Autores principales: Revie, Nicole M., Robbins, Nicole, Whitesell, Luke, Frost, John R., Appavoo, Solomon D., Yudin, Andrei K., Cowen, Leah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142304/
https://www.ncbi.nlm.nih.gov/pubmed/32269162
http://dx.doi.org/10.1128/mSphere.00256-20