Genotype-Guided Thiopurine Dosing Does not Lead to Additional Costs in Patients With Inflammatory Bowel Disease

BACKGROUND AND AIMS: Decreased thiopurine S-methyltransferase [TPMT] enzyme activity increases the risk of haematological adverse drug reactions [ADRs] in patients treated with thiopurines. Clinical studies have shown that in patients with inflammatory bowel disease [IBD], pharmacogenetic TPMT-guide...

Descripción completa

Detalles Bibliográficos
Autores principales: Sluiter, Reinier L, van Marrewijk, Corine, de Jong, Dirk, Scheffer, Hans, Guchelaar, Henk-Jan, Derijks, Luc, Wong, Dennis R, Hooymans, Piet, Vermeulen, Sita H, Verbeek, André L M, Franke, Barbara, van der Wilt, Gert Jan, Kievit, Wietske, Coenen, Marieke J H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142326/
https://www.ncbi.nlm.nih.gov/pubmed/30698675
http://dx.doi.org/10.1093/ecco-jcc/jjz009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142326/
https://www.ncbi.nlm.nih.gov/pubmed/30698675
http://dx.doi.org/10.1093/ecco-jcc/jjz009

Ejemplares similares