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Astrocytes Are Required for Oligodendrocyte Survival and Maintenance of Myelin Compaction and Integrity

Astrocytes have been implicated in regulating oligodendrocyte development and myelination in vitro, although their functions in vivo remain less well defined. Using a novel approach to locally ablate GFAP+ astrocytes, we demonstrate that astrocytes are required for normal CNS myelin compaction durin...

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Detalles Bibliográficos
Autores principales: Tognatta, Reshmi, Karl, Molly T., Fyffe-Maricich, Sharyl L., Popratiloff, Anastas, Garrison, Eric D., Schenck, Jessica K., Abu-Rub, Mohammad, Miller, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142332/
https://www.ncbi.nlm.nih.gov/pubmed/32300294
http://dx.doi.org/10.3389/fncel.2020.00074