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Astrocytes Are Required for Oligodendrocyte Survival and Maintenance of Myelin Compaction and Integrity
Astrocytes have been implicated in regulating oligodendrocyte development and myelination in vitro, although their functions in vivo remain less well defined. Using a novel approach to locally ablate GFAP+ astrocytes, we demonstrate that astrocytes are required for normal CNS myelin compaction durin...
Autores principales: | Tognatta, Reshmi, Karl, Molly T., Fyffe-Maricich, Sharyl L., Popratiloff, Anastas, Garrison, Eric D., Schenck, Jessica K., Abu-Rub, Mohammad, Miller, Robert H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142332/ https://www.ncbi.nlm.nih.gov/pubmed/32300294 http://dx.doi.org/10.3389/fncel.2020.00074 |
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