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Genetic Evolution of Mycobacterium abscessus Conferring Clarithromycin Resistance during Long-Term Antibiotic Therapy

OBJECTIVES: Clarithromycin is recommended as the core agent for treating M. abscessus infections, which usually calls for at least one year of treatment course, facilitating the development of resistance. This study aimed to identify the underlying mechanism of in vivo development of clarithromycin...

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Detalles Bibliográficos
Autores principales: Li, Bing, Guo, Qi, Mao, Yanhua, Zou, Yuzhen, Zhang, Yongjie, Zhang, Zhemin, Chu, Haiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142343/
https://www.ncbi.nlm.nih.gov/pubmed/32300380
http://dx.doi.org/10.1155/2020/7623828