Cargando…

Transposon mutagenesis in Mycobacterium kansasii links a small RNA gene to colony morphology and biofilm formation and identifies 9,885 intragenic insertions that do not compromise colony outgrowth

Mycobacterium kansasii (Mk) is a resilient opportunistic human pathogen that causes tuberculosis‐like chronic pulmonary disease and mortality stemming from comorbidities and treatment failure. The standard treatment of Mk infections requires costly, long‐term, multidrug courses with adverse side eff...

Descripción completa

Detalles Bibliográficos
Autores principales: Budell, William C., Germain, Gabrielle A., Janisch, Niklas, McKie‐Krisberg, Zaid, Jayaprakash, Anitha D., Resnick, Andrew E., Quadri, Luis E. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142372/
https://www.ncbi.nlm.nih.gov/pubmed/32083796
http://dx.doi.org/10.1002/mbo3.988