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Heredity Indexes for Estimating Heritability Using Known and Unknown Family Data Based on the Model of Polygenic Inheritance
OBJECTIVE: To establish a model for estimating genetic risk using known and unknown family data. METHODS: Four simulated datasets were generated for four paternal and maternal chromosomes. The simulated data for children were generated from the parental data according to the Mendelian law. The corre...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142385/ https://www.ncbi.nlm.nih.gov/pubmed/32300373 http://dx.doi.org/10.1155/2020/7243976 |