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Protective Effect of Low-Molecular-Weight Fucoidan on Radiation-Induced Fibrosis Through TGF-β1/Smad Pathway-Mediated Inhibition of Collagen I Accumulation

Radiation-induced fibrosis (RIF) occurs after radiation therapy in normal tissues due to excessive production and deposition of extracellular matrix proteins and collagen, possibly resulting in organ function impairment. This study investigates the effects of low-molecular-weight fucoidan (LMF) on i...

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Detalles Bibliográficos
Autores principales: Wu, Szu-Yuan, Chen, Yu-Ting, Tsai, Guo-Yu, Hsu, Fu-Yin, Hwang, Pai-An
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142431/
https://www.ncbi.nlm.nih.gov/pubmed/32120789
http://dx.doi.org/10.3390/md18030136